CD27 (21-191, His-tag) Human Protein
CAT#: AR50534PU-N
CD27 (21-191, His-tag) human recombinant protein, 0.5 mg
Size: 100 ug
Need it in bulk or customized? Get a free quote |
CNY 14,920.00
货期*
详询
规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSHMTPAPK SCPERHYWAQ GKLCCQMCEP GTFLVKDCDQ HRKAAQCDPC IPGVSFSPDH HTRPHCESCR HCNSGLLVRN CTITANAECA CRNGWQCRDK ECTECDPLPN PSLTARSSQA LSPHPQPTHL PYVSEMLEAR TAGHMQTLAD FRQLPARTLS THWPPQRSLC SSDFIR
|
Tag | His-tag |
Predicted MW | 21.8 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant human CD27 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001233 |
Locus ID | 939 |
UniProt ID | P26842 |
Cytogenetics | 12p13.31 |
Synonyms | TNFRSF7, CD27L receptor, T14 |
Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
Documents
FAQs |
SDS |
Customer
Reviews
Loading...