Prohibitin / PHB (1-272, His-tag) Human Protein
CAT#: AR50811PU-N
Prohibitin / PHB (1-272, His-tag) human recombinant protein, 0.25 mg
Size: 50 ug
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CNY 14,920.00
货期*
详询
规格
Cited in 2 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MAAKVFESIG KFGLALAVAG GVVNSALYNV DAGHRAVIFD RFRGVQDIVV GEGTHFLIPW VQKPIIFDCR SRPRNVPVIT GSKDLQNVNI TLRILFRPVA SQLPRIFTSI GEDYDERVLP SITTEILKSV VARFDAGELI TQRELVSRQV SDDLTERAAT FGLILDDVSL THLTFGKEFT EAVEAKQVAQ QEAERARFVV EKAEQQKKAA IISAEGDSKA AELIANSLAT AGDGLIELRK LEAAEDIAYQ LSRSRNITYL PAGQSVLLQL PQ
|
Tag | His-tag |
Predicted MW | 31.9 kDa |
Concentration | lot specific |
Purity | >85% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl |
Preparation | Liquid purified protein |
Protein Description | Recombinant human PHB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001268425 |
Locus ID | 5245 |
UniProt ID | P35232 |
Cytogenetics | 17q21.33 |
Synonyms | PHB1 |
Summary | This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
Prohibitin‐1 Is a Dynamically Regulated Blood Protein With Cardioprotective Effects in Sepsis
,null,
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
,PubMed ID 34219469
[PHB]
|
Regulation of Syk by Phosphorylation on Serine in the Linker Insert *
,null,
The Journal of Biological Chemistry
,PubMed ID 20956537
[PHB]
|
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