TUBB3 / TUBB4 (1-450, His-tag) Human Protein
CAT#: AR50820PU-N
TUBB3 / TUBB4 (1-450, His-tag) human recombinant protein, 0.25 mg
Size: 50 ug
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CNY 17,930.00
货期*
详询
规格
Cited in 6 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSMREIVHI QAGQCGNQIG AKFWEVISDE HGIDPSGNYV GDSDLQLERI SVYYNEASSH KYVPRAILVD LEPGTMDSVR SGAFGHLFRP DNFIFGQSGA GNNWAKGHYT EGAELVDSVL DVVRKECENC DCLQGFQLTH SLGGGTGSGM GTLLISKVRE EYPDRIMNTF SVVPSPKVSD TVVEPYNATL SIHQLVENTD ETYCIDNEAL YDICFRTLKL ATPTYGDLNH LVSATMSGVT TSLRFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTARG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVATVF RGRMSMKEVD EQMLAIQSKN SSYFVEWIPN NVKVAVCDIP PRGLKMSSTF IGNSTAIQEL FKRISEQFTA MFRRKAFLHW YTGEGMDEME FTEAESNMND LVSEYQQYQD ATAEEEGEMY EDDEEESEAQ GPK
|
Tag | His-tag |
Predicted MW | 52.8 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1 mM DTT |
Preparation | Liquid purified protein |
Protein Description | Recombinant human TUBB3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001184110 |
Locus ID | 10381 |
UniProt ID | Q13509 |
Cytogenetics | 16q24.3 |
Synonyms | beta-4; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; TUBB4 |
Summary | This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Gap junction, Pathogenic Escherichia coli infection |
Citations (6)
The use of this Proteins has been cited in the following citations: |
---|
Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism
,null,
Molecular Therapy Oncolytics
,PubMed ID 30847383
[TUBB3]
|
Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes
,null,
Human Molecular Genetics
,PubMed ID 26130693
[TUBB3]
|
Coordinated Interaction of Down Syndrome Cell Adhesion Molecule (DSCAM) nd Deleted in Colorectal Cancer (DCC) with Dynamic TUBB3 Mediates Netrin-1-Induced Axon Branching
,null,
Neuroscience
,PubMed ID 25754961
[TUBB3]
|
EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein.
,null,
Molecular cancer therapeutics
,PubMed ID 24980949
[TUBB3]
|
Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance
,null,
Journal of Cell Science
,PubMed ID 23641072
[TUBB3]
|
Altered TUBB3 expression contributes to the epothilone response of mitotic cells
,null,
British Journal of Cancer
,PubMed ID 23321512
[TUBB3]
|
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