CD201 / EPCR (18-210, His-tag) Human Protein
CAT#: AR51458PU-N
CD201 / EPCR (18-210, His-tag) human recombinant protein, 0.5 mg
Size: 100 ug
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CNY 14,920.00
货期*
详询
规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSSQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTS
|
Tag | His-tag |
Predicted MW | 24.4 kDa |
Concentration | lot specific |
Purity | >80% by SDS - PAGE |
Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M Urea |
Preparation | Liquid purified protein |
Protein Description | Recombinant human PROCR protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_006395 |
Locus ID | 10544 |
UniProt ID | Q9UNN8 |
Cytogenetics | 20q11.22 |
Synonyms | PROCR, Endothelial protein C receptor, APC receptor |
Summary | The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
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