Agouti-related protein / AGRP (21-132, His-tag) Human Protein
CAT#: AR51838PU-S
Agouti-related protein / AGRP (21-132, His-tag) human recombinant protein, 20 µg
Size: 100 ug
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CNY 8,900.00
货期*
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSHMAQMGL APMEGIRRPD QALLPELPGL GLRAPLKKTT AEQAEEDLLQ EAQALAEVLD LQDREPRSSR RCVRLHESCL GQQVPCCDPC ATCYCRFFNA FCYCRKLGTA MNPCSRT
|
Tag | His-tag |
Predicted MW | 15.1 kDa |
Concentration | lot specific |
Purity | >85% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl (pH 8.5) containing 20% glycerol, 1 mM DTT |
Preparation | Liquid purified protein |
Protein Description | Recombinant human AGRP, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001129 |
Locus ID | 181 |
UniProt ID | O00253, C6SUN5 |
Cytogenetics | 16q22.1 |
Synonyms | AGRT; ART; ASIP2 |
Summary | This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Adipocytokine signaling pathway |
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