UCHL1 / PGP9.5 (1-223, His-tag) Mouse Protein
CAT#: AR51909PU-N
UCHL1 / PGP9.5 (1-223, His-tag) mouse recombinant protein, 0.5 mg
Size: 100 ug
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CNY 14,920.00
货期*
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规格
Cited in 1 publication. |
Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSMQLKPME INPEMLNKVL AKLGVAGQWR FADVLGLEEE TLGSVPSPAC ALLLLFPLTA QHENFRKKQI EELKGQEVSP KVYFMKQTIG NSCGTIGLIH AVANNQDKLE FEDGSVLKQF LSETEKLSPE DRAKCFEKNE AIQAAHDSVA QEGQCRVDDK VNFHFILFNN VDGHLYELDG RMPFPVNHGA SSEDSLLQDA AKVCREFTER EQGEVRFSAV ALCKAA
|
Tag | His-tag |
Predicted MW | 27.2 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate buffered saline containing 10% glycerol, 1 mM DTT |
Preparation | Liquid purified protein |
Protein Description | Recombinant mouse Uchl1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_035800 |
Locus ID | 22223 |
UniProt ID | Q9R0P9 |
Cytogenetics | 5 35.95 cM |
Synonyms | AW822034; C88048; gad; PGP 9.5; PGP9.5; R75593; UCH-L1; UCHL-1 |
Summary | Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (PubMed:12913066). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (PubMed:12913066). The homodimer may have ATP-independent ubiquitin ligase activity (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
,null,
Human Molecular Genetics
,PubMed ID 24852371
[Uchl1]
|
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