CD137 / TNFRSF9 (18-186, hIgG-His-tagged) Human Protein
CAT#: AR52030PU-S
CD137 / TNFRSF9 (18-186, hIgG-His-tagged) human protein, 50 µg
Size: 250 ug
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CNY 8,900.00
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | Insect |
Expression cDNA Clone or AA Sequence |
ADLFERTRSL QDPCSNCPAG TFCDNNRNQI CSPCPPNSFS SAGGQRTCDI CRQCKGVFRT RKECSSTSNA ECDCTPGFHC LGAGCSMCEQ DCKQGQELTK KGCKDCCFGT FNDQKRGICR PWTNCSLDGK SVLVNGTKER DVVCGPSPAD LSPGASSVTP PAPAREPGHS PQLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
|
Tag | hIgG-His-tag |
Predicted MW | 45.3 kDa |
Concentration | lot specific |
Purity | >90% by SDS – PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Preparation | Liquid purified protein |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Endotoxin | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Reference Data | |
RefSeq | NP_001552 |
Locus ID | 3604 |
UniProt ID | Q07011 |
Cytogenetics | 1p36.23 |
Synonyms | 4-1BB; CD137; CDw137; ILA |
Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction |
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