PLA2G1B (His-tagged Fusion Protein) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MRGSHHHHHH GMASHMAVWQ FRKMIKCVIP GSDPFLEYNN YGCYCGLGGS GTPVDELDKC CQTHDNCYDQ AKKLDSCKFL LDNPYTHTYS YSCSGSAITC SSKNKECEAF ICNCDRNAAI CFSKAPYNKA HKNLDTKKYC QS
Tag	His-tag
Concentration	lot specific
Purity	>95% > 95%
Buffer	Presentation State: Purified State: Lyophilized (0.4 um filtered) purified protein. Buffer System: 0.05 M Acetate buffer pH4
Preparation	Lyophilized (0.4 um filtered) purified protein.
Applications	Western Blot.
Protein Description	Total 142 AA. MW: 16 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
Note	Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Storage	Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_000919
Locus ID	5319
UniProt ID	P04054
Cytogenetics	12q24.31
Synonyms	PLA2G1B, PLA2, PLA2A, PPLA2, Phospholipase A2, Group IB phospholipase A2
Summary	This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
Protein Families	Western Blot.
Protein Pathways	alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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