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Mu Opioid Receptor (OPRM1) (NM_000914) Human Recombinant Protein
CAT＃: TP310383
Recombinant protein of human opioid receptor, mu 1 (OPRM1), transcript variant MOR-1, 20 µg
View other "Mu Opioid Receptor" proteins (13)
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CNY 2,900.00
| Cited in 1 publication. |
Product images
CNY 600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC210383 protein sequence
Red=Cloning site Green=Tags(s) MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITA ITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTI LCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATT KYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRI TRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFR EFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 44.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_000905 |
| Locus ID | 4988 |
| UniProt ID | P35372 |
| Refseq Size | 15279 |
| Cytogenetics | 6q25.2 |
| Refseq ORF | 1200 |
| Synonyms | LMOR; M-OR-1; MOP; MOR; MOR1; OPRM |
| Summary | This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013] |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
The Mu Opioid Receptor Promotes Opioid and Growth Factor-Induced Proliferation, Migration and Epithelial Mesenchymal Transition (EMT) in Human Lung Cancer
,null,
PLoS ONE
,PubMed ID 24662916
[OPRM1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400332 | OPRM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC423445 | OPRM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC428783 | OPRM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC428785 | OPRM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC428788 | OPRM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC428790 | OPRM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400332 | Transient overexpression lysate of opioid receptor, mu 1 (OPRM1), transcript variant MOR-1 |
CNY 3,080.00 |
|
| LY423445 | Transient overexpression lysate of opioid receptor, mu 1 (OPRM1), transcript variant MOR-1X |
CNY 4,840.00 |
|
| LY428783 | Transient overexpression lysate of opioid receptor, mu 1 (OPRM1), transcript variant MOR-1H |
CNY 3,080.00 |
|
| LY428785 | Transient overexpression lysate of opioid receptor, mu 1 (OPRM1), transcript variant MOR-1G2 |
CNY 3,080.00 |
|
| LY428788 | Transient overexpression lysate of opioid receptor, mu 1 (OPRM1), transcript variant MOR-1B3 |
CNY 3,080.00 |
|
| LY428790 | Transient overexpression lysate of opioid receptor, mu 1 (OPRM1), transcript variant MOR-1B5 |
CNY 3,080.00 |
|
| PH310383 | OPRM1 MS Standard C13 and N15-labeled recombinant protein (NP_000905) |
CNY 19,520.00 |
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