Aminopeptidase A (ENPEP) (NM_001977) Human Recombinant Protein
CAT#: TP310521
Recombinant protein of human glutamyl aminopeptidase (aminopeptidase A) (ENPEP), 20 µg
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Cited in 1 publication. |
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC210521 protein sequence
Red=Cloning site Green=Tags(s) MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHLPSSTASPSGP PAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETR ITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTE NGRVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSV PMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIA IPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFAS FFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLE DWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRF LLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVN YEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVT YIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQ WLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLK DTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMES FFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 109.1 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001968 |
Locus ID | 2028 |
UniProt ID | Q07075 |
Refseq Size | 5004 |
Cytogenetics | 4q25 |
Refseq ORF | 2871 |
Synonyms | APA; CD249; gp160 |
Summary | The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane |
Protein Pathways | Renin-angiotensin system |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
Lisdexamfetamine prodrug activation by peptidase-mediated hydrolysis in the cytosol of red blood cells
,null,
Neuropsychiatric Disease and Treatment
,PubMed ID 25489246
[ENPEP]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC419610 | ENPEP HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY419610 | Transient overexpression lysate of glutamyl aminopeptidase (aminopeptidase A) (ENPEP) |
CNY 3,080.00 |
|
PH310521 | ENPEP MS Standard C13 and N15-labeled recombinant protein (NP_001968) |
CNY 19,520.00 |
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