PAX3 (NM_181457) Human Recombinant Protein
CAT#: TP315181
Purified recombinant protein of Homo sapiens paired box 3 (PAX3), transcript variant PAX3, 20 µg
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC215181 representing NM_181457
Red=Cloning site Green=Tags(s) MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPC VISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKD AVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSE PDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGA NQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDS SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLE PTTTVSASCSQRLDHMKSLDSLPTSQSYCPPTYSTTGYSMDPVTGYQYGQYGQSKPWTF TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 52.8 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_852122 |
Locus ID | 5077 |
UniProt ID | P23760 |
Refseq Size | 3193 |
Cytogenetics | 2q36.1 |
Refseq ORF | 1437 |
Synonyms | CDHS; HUP2; WS1; WS3 |
Summary | This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008] |
Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC405766 | PAX3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC405767 | PAX3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC405768 | PAX3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC405770 | PAX3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY405766 | Transient overexpression lysate of paired box 3 (PAX3), transcript variant PAX3 |
CNY 4,840.00 |
|
LY405767 | Transient overexpression lysate of paired box 3 (PAX3), transcript variant PAX3D |
CNY 4,840.00 |
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LY405768 | Transient overexpression lysate of paired box 3 (PAX3), transcript variant PAX3E |
CNY 4,840.00 |
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LY405770 | Transient overexpression lysate of paired box 3 (PAX3), transcript variant PAX3G |
CNY 3,080.00 |
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PH315181 | PAX3 MS Standard C13 and N15-labeled recombinant protein (NP_852122) |
CNY 14,250.00 |
|
TP760417 | Purified recombinant protein of Human paired box 3 (PAX3), transcript variant PAX3D, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2,040.00 |