FOXP3 (NM_014009) Human Recombinant Protein
CAT#: TP317580
Recombinant protein of human forkhead box P3 (FOXP3), transcript variant 1, 20 µg
View other "FOXP3" proteins (6)
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CNY 2,900.00
Cited in 2 publications. |
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC217580 representing NM_014009
Red=Cloning site Green=Tags(s) MPNPRPGKPSAPSLALGPSPGASPSWRAAPKASDLLGARGPGGTFQGRDLRGGAHASSSSLNPMPPSQLQ LPTLPLVMVAPSGARLGPLPHLQALLQDRPHFMHQLSTVDAHARTPVLQVHPLESPAMISLTPPTTATGV FSLKARPGLPPGINVASLEWVSREPALLCTFPNPSAPRKDSTLSAVPQSSYPLLANGVCKWPGCEKVFEE PEDFLKHCQADHLLDEKGRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASSDKGSC CIVAAGSQGPVVPAWSGPREAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPPFTYATLIRWAI LEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKKRSQR PSRCSNPTPGP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 47.1 kDa |
Concentration | >0.1 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Bioactivity | Enzyme substrate (PMID: 30054205) |
Reference Data | |
RefSeq | NP_054728 |
Locus ID | 50943 |
UniProt ID | Q9BZS1 |
Refseq Size | 1869 |
Cytogenetics | Xp11.23 |
Refseq ORF | 1293 |
Synonyms | AIID; DIETER; IPEX; JM2; PIDX; XPID |
Summary | The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
Protein Families | Transcription Factors |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells
,Stathopoulou, C;Gangaplara, A;Mallett, G;Flomerfelt, FA;Liniany, LP;Knight, D;Samsel, LA;Berlinguer-Palmini, R;Yim, JJ;Felizardo, TC;Eckhaus, MA;Edgington-Mitchell, L;Martinez-Fabregas, J;Zhu, J;Fowler, DH;van Kasteren, SI;Laurence, A;Bogyo, M;Watts, C;Shevach, EM;Amarnath, S;,
Immunity
,PubMed ID 30054205
[FOXP3]
|
Functional characterization of Foxp3-specific spontaneous immune responses
,S K Larsen, S Munir, A Woetmann, T M Frøsig, N Odum, + et al.,
Leukemia doi:10.1038/leu.2013.196
,PubMed ID 23812418
[Foxp3]
|
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Other Versions
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LC402270 | FOXP3 HEK293T cell transient overexpression lysate (as WB positive control) |
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PH317580 | FOXP3 MS Standard C13 and N15-labeled recombinant protein (NP_054728) |
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