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Dynamin 2 (DNM2) (NM_001005360) Human Recombinant Protein
CAT＃: TP323585
Recombinant protein of human dynamin 2 (DNM2), transcript variant 1, 20 µg
View other "Dynamin 2" proteins (9)
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CNY 2,900.00
CNY 6,650.00
| Cited in 1 publication. |
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CNY 600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC223585 protein sequence
Red=Cloning site Green=Tags(s) MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLI LQLIFSKTEHAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGI TKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLM DEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKT LNQQLTNHIRESLPALRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQ VDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNH EDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKE KKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKD QAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLY SSADQSSLMEESADQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPTPQRR PVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFSAPPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPP GIPPGVPSRRPPAAPSRPTIIRPAEPSLLD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 97.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001005360 |
| Locus ID | 1785 |
| UniProt ID | P50570 |
| Refseq Size | 3684 |
| Cytogenetics | 19p13.2 |
| Refseq ORF | 2610 |
| Synonyms | CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5 |
| Summary | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010] |
| Protein Families | Transcription Factors |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
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A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy
,Puri, C;Manni, MM;Vicinanza, M;Hilcenko, C;Zhu, Y;Runwal, G;Stamatakou, E;Menzies, FM;Mamchaoui, K;Bitoun, M;Rubinsztein, DC;,
Dev. Cell
,PubMed ID 32315611
[DNM2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC417632 | DNM2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC423697 | DNM2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC423698 | DNM2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LY417632 | Transient overexpression lysate of dynamin 2 (DNM2), transcript variant 3 |
CNY 3,080.00 |
|
| LY423697 | Transient overexpression lysate of dynamin 2 (DNM2), transcript variant 1 |
CNY 4,840.00 |
|
| LY423698 | Transient overexpression lysate of dynamin 2 (DNM2), transcript variant 2 |
CNY 4,840.00 |
|
| PH308525 | DNM2 MS Standard C13 and N15-labeled recombinant protein (NP_004936) |
CNY 14,250.00 |
|
| PH323585 | DNM2 MS Standard C13 and N15-labeled recombinant protein (NP_001005360) |
CNY 19,520.00 |
|
| TP308525 | Recombinant protein of human dynamin 2 (DNM2), transcript variant 3, 20 µg |
CNY 2,900.00 |
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