Rassf7 (NM_025886) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR205353 representing NM_025886 Red=Cloning site Green=Tags(s) MVLELVAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQ ATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKPSAIPGREPRKALTFNLRCPKLVPS PSIPEPAALVGPIPDGFADLQDLELRIQRNTEELGHEAFWEQELQREQAREREGQARLQALSAATAEHAA RLEALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLATQERHSLEMQGTLALVSQALEAAEHALQA QAQELEELNRELRQCNLQQFIQQTGAALPPPPPQLDRTIPSTQDLLSPNRGELQGVPQSHILVSSLSPEV PPMRQSSWR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	39.7 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_080162
Locus ID	66985
UniProt ID	Q9DD19
Refseq Size	1530
Cytogenetics	7 F5
Refseq ORF	1077
Synonyms	2400009B11Rik; AW210608
Summary	Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity).[UniProtKB/Swiss-Prot Function]

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