C80913 (BC023029) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR207303 protein sequence Red=Cloning site Green=Tags(s) MVPFGPLAFMPGKLVHTNEVTVLLGDNWFAKCSAKQAVGLVEHRKEHVRKTIDDFKKVLKNFESRVEFTE DLQKMSDAAGDFVDIREEIKSDFEFKGKQRIAHKPHSKPKTSDIFEADFENGVKPKDTFDADELWARLEE LERQEELLGELESKPDTVIANGEDRVSSEEEKEGADTGVNVVSPVTDSSAASSCKRRAGNAGLPNGQVNS LNYSVNGSNSYHSNKDDDEEEDDDDDDDDEDDDNESDHAISADNSIPTIYFSHTVEPKRVRINTGKNTTL KFSEKKEEAKRKRKSGAGSHATHELPAIKSPADIYRVFVDVVNGEYVPHKSILKSRSRENSVCSDTSESS AADVEDRRGLLRSTSSEEAVATEAGGSSLDELQENHPKKPLPSGVSEAFSGTVIEKEFLSPSLAPYSAIA HHALPTIPERKEVPSEVSEEPTKRVSKFRAARLQQRS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	50.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
Locus ID	19777
UniProt ID	Q3TLD5
Refseq Size	2462
Cytogenetics	7 B3
Refseq ORF	1371
Synonyms	Rmp, NNX3
Summary	Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region (By similarity).[UniProtKB/Swiss-Prot Function]

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