Dnaja3 (NM_023646) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR215670 representing NM_023646 Red=Cloning site Green=Tags(s) MAAWCSPRWLRVAVGTPRLPAAAGRGVQQPQGGVVATSLCRKLCVSAFGLSMGAHGPRALLTLRPGVRLT GTKSFPFVCTTSFHTSASLAKDDYYQILGVPRNASQKDIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAE AYEVLSDEVKRKQYDAYGSAGFDPGTSSSGQGYWRGGPSVDPEELFRKIFGEFSSSPFGDFQNVFDQPQE YIMELTFNQAAKGVNKEFTVNIMDTCERCDGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGG RGSIITNPCVVCRGAGQAKQKKRVTIPVPAGVEDGQTVRMPVGKREIFVTFRVQKSPVFRRDGADIHSDL FISIAQAILGGTAKAQGLYETINVTIPAGIQTDQKIRLTGKGIPRINSYGYGDHYIHIKIRVPKRLSSRQ QNLILSYAEDETDVEGTVNGVTHTSTGGRTMDSSAGSKDRREAGEDNEGFLSKLKKIFTS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	52.9 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_076135
Locus ID	83945
UniProt ID	Q99M87
Refseq Size	2666
Cytogenetics	16 2.46 cM
Refseq ORF	1440
Synonyms	1200003J13Rik; 1810053A11Rik; C81173; Tid-1; Tid1l
Summary	Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity (By similarity). Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.[UniProtKB/Swiss-Prot Function]

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