Tctn1 (NM_001039153) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR218335 representing NM_001039153 Red=Cloning site Green=Tags(s) MGSRGLPPLLLVLLNCYTSSSTQVIAIPAAATPAVTKEDLNSTKATPTTLQPSLSPRTPGTPRAPERSGP RPTPVTDVAALCVCDLLPAQCDVNCCCDPDCSPADFSIFSACSVPVVTGDRQFCSQKAAFYSMNLTADPP HRDFKLIDQINPSVFCIHISNYKPALSFANPEVPDENNFDRLMQTSGGFTLSAESAVPSTAASDGPQPTK YEYGAPLQTAGASSGSFLKLPSPLTSSLCADQNPAAFLVSQAFECSRRVDIEQCEGMEALSMAHYSSPAI LRVPNSMTQVSIKIQSVMYRSLNHTLTQLEGHGVLRPSLVSTGQDRLCSNVVLQVKYSLLYTATGQIHEA GLSLVLGTLSSAVSLLQQKFEIHFIQHGTKPVPLSGNPGYRVGLPLAAGFQPQKGSGIIQTTNRQGQFTI LRSTSQQDCLASEGLRTPVLFGYNVQSGCQLRLTGTIPCGLLAQKVQDLLRGQAFPDYVAAFGNSRAQDV QDWVPVHFVTYSSNMKGSCQLPVALAIEVKWTKYGSLLNPQARIVNVTAQLVSVPEPLPGPERTVVISTA VTFVDVSAPAEAGFRAPPTINARLPFSFFFPFV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	63.9 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001034242
Locus ID	654470
UniProt ID	Q8BZ64
Refseq Size	2068
Cytogenetics	5 F
Refseq ORF	1779
Synonyms	G730031O11Rik; Tect1
Summary	Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23.[UniProtKB/Swiss-Prot Function]

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