B7H3 (CD276) (NM_001024736) Human Recombinant Protein
CAT#: TP700270
Purified recombinant protein of human CD276 molecule (CD276), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC215064, encoding the region (Leu29 – Ala466) of human CD276
|
Tag | C-DDK/His |
Predicted MW | 49 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | PBS, pH 7.4, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001019907 |
Locus ID | 80381 |
UniProt ID | Q5ZPR3 |
Refseq Size | 3419 |
Cytogenetics | 15q24.1 |
Refseq ORF | 1602 |
Synonyms | 4Ig-B7-H3; B7-H3; B7H3; B7RP-2 |
Summary | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC410803 | CD276 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC422539 | CD276 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC425464 | CD276 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY410803 | Transient overexpression lysate of CD276 molecule (CD276), transcript variant 2 |
CNY 3,080.00 |
|
LY422539 | Transient overexpression lysate of CD276 molecule (CD276), transcript variant 1 |
CNY 4,840.00 |
|
LY425464 | Transient overexpression lysate of CD276 molecule (CD276), transcript variant 1 |
CNY 3,080.00 |
|
PH315291 | CD276 MS Standard C13 and N15-labeled recombinant protein (NP_079516) |
CNY 19,520.00 |
|
TP315291 | Recombinant protein of human CD276 molecule (CD276), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
TP723935 | Human B7-H3 Protein, mFc-His Tag |
CNY 5,876.00 |