United States
Germany
Japan
United Kingdom
China
OGG1 (NM_002542) Human Recombinant Protein
CAT＃: TP720109
Recombinant protein of human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1a
View other "OGG1" proteins (11)
|
Need it in bulk or customized? Get a free quote |
CNY 3,140.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
Met1-Gly345
|
| Tag | N-GST |
| Predicted MW | 65.1 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Supplied as a 0.2 um filtered solution of 20mMTris-HCl,150mMNacl,1mMEDTA,pH8.5. |
| Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
| Reference Data | |
| RefSeq | NP_002533 |
| Locus ID | 4968 |
| UniProt ID | O15527, E5KPN1 |
| Cytogenetics | 3p25.3 |
| Synonyms | HMMH; HOGG1; MUTM; OGH1 |
| Summary | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008] |
| Protein Families | Druggable Genome |
| Protein Pathways | Base excision repair |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Reactive oxygen species induced by icaritin promote DNA strand breaks and apoptosis in human cervical cancer cells
,Chen, X;Song, L;Hou, Y;Li, F;,
Oncol. Rep.
,PubMed ID 30431140
[OGG1]
|
Documents
| FAQs |
| SDS |
Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC413811 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC413813 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC413815 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC413816 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC413835 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY413811 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a |
CNY 4,840.00 |
|
| LY413813 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2b |
CNY 3,080.00 |
|
| LY413815 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2d |
CNY 3,080.00 |
|
| LY413816 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2e |
CNY 3,080.00 |
|
| LY413835 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1b |
CNY 3,080.00 |
|
| TP760967 | Purified recombinant protein of Human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a, full length, with N-terminal HIS tag, expressed in E. coli, 50ug |
CNY 2,040.00 |
