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Cathepsin B (CTSB) (NM_001908) Human Recombinant Protein
CAT＃: TP720340
Recombinant protein of human cathepsin B (CTSB), transcript variant 1
View other "Cathepsin B" proteins (20)
|
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CNY 1,800.00
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热销推荐Specifications
| Product Data | |
| Species | Human |
| Expression cDNA Clone or AA Sequence |
Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
|
| Tag | C-6xHis |
| Predicted MW | 36.9 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Supplied as a 0.2 um filtered solution of PBS, pH 7.4. |
| Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
| Reference Data | |
| RefSeq | |
| Locus ID | 1508 |
| UniProt ID | P07858 |
| Cytogenetics | 8p23.1 |
| Synonyms | APPS; CPSB; RECEUP |
| Summary | This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Sep 2020] |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Antigen processing and presentation, Lysosome |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403447 | CTSB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC407800 | CTSB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC407801 | CTSB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC407802 | CTSB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC419666 | CTSB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC430182 | CTSB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403447 | Transient overexpression lysate of cathepsin B (CTSB), transcript variant 5 |
CNY 3,080.00 |
|
| LY407800 | Transient overexpression lysate of cathepsin B (CTSB), transcript variant 2 |
CNY 3,080.00 |
|
| LY407801 | Transient overexpression lysate of cathepsin B (CTSB), transcript variant 3 |
CNY 3,080.00 |
|
| LY407802 | Transient overexpression lysate of cathepsin B (CTSB), transcript variant 4 |
CNY 3,080.00 |
|
| LY419666 | Transient overexpression lysate of cathepsin B (CTSB), transcript variant 1 |
CNY 3,080.00 |
|
| LY430182 | Transient overexpression lysate of cathepsin B (CTSB), transcript variant 2 |
CNY 3,080.00 |
|
| PH310578 | CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680093) |
CNY 19,520.00 |
|
| PH322289 | CTSB MS Standard C13 and N15-labeled recombinant protein (NP_001899) |
CNY 19,520.00 |
|
| PH322463 | CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680092) |
CNY 14,250.00 |
|
| PH322764 | CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680091) |
CNY 14,250.00 |
|
| TP310578 | Recombinant protein of human cathepsin B (CTSB), transcript variant 5, 20 µg |
CNY 2,900.00 |
|
| TP322289 | Recombinant protein of human cathepsin B (CTSB), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP322463 | Purified recombinant protein of Homo sapiens cathepsin B (CTSB), transcript variant 4, 20 µg |
CNY 2,900.00 |
|
| TP322764 | Purified recombinant protein of Homo sapiens cathepsin B (CTSB), transcript variant 3, 20 µg |
CNY 2,900.00 |
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