Apolipoprotein H (APOH) (NM_000042) Human Recombinant Protein
CAT#: TP720364XL
Recombinant protein of human apolipoprotein H (beta-2-glycoprotein I) (APOH)
Need it in bulk or customized? Get a free quote |
CNY 26,600.00
货期*
2周
规格
经常一起买 (1)
APOH mouse monoclonal antibody, clone OTI4A11 (formerly 4A11)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gly20-Ser345
|
Tag | C-His |
Predicted MW | 37.3 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_000033 |
Locus ID | 350 |
UniProt ID | P02749, A0A384NKM6 |
Cytogenetics | 17q24.2 |
Synonyms | B2G1; B2GP1; BG |
Summary | Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019] |
Protein Families | Druggable Genome, Secreted Protein |
Documents
FAQs |
SDS |
其它Apolipoprotein H产品
Customer
Reviews
Loading...