Glutamine Synthetase (GLUL) (NM_002065) Human Recombinant Protein
CAT#: TP720579M
Recombinant protein of human glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 1
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CNY 7,220.00
货期*
2周
规格
经常一起买 (1)
GLUL mouse monoclonal antibody, clone OTI1F4 (formerly 1F4)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Thr2-Asn373
|
Tag | C-His |
Predicted MW | 43.0 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 200mM NaCl, 50mM Imidazole, pH 8.0. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_002056 |
Locus ID | 2752 |
UniProt ID | P15104, A8YXX4 |
Cytogenetics | 1q25.3 |
Synonyms | GLNS; GS; PIG43; PIG59 |
Summary | The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
Protein Pathways | Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Nitrogen metabolism |
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