TIMP2 (NM_003255) Human Recombinant Protein
CAT#: TP720667XL
Purified recombinant protein of Human TIMP metallopeptidase inhibitor 2 (TIMP2)
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CNY 26,600.00
货期*
2周
规格
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经常一起买 (1)
TIMP2 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Cys27-Pro220
|
Tag | C-His |
Predicted MW | 22.79 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_003246 |
Locus ID | 7077 |
UniProt ID | P16035, A0A140VK57 |
Refseq Size | 3670 |
Cytogenetics | 17q25.3 |
Refseq ORF | 660 |
Synonyms | CSC-21K; DDC8 |
Summary | This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Secreted Protein |
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