Purified recombinant protein of Mouse cathepsin L (Ctsl) (Ctsl) (NM_009984) Human Recombinant Protein
CAT#: TP720793
Purified recombinant protein of Mouse cathepsin L (Ctsl)
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CNY 3,140.00
货期*
2周
规格
Cited in 4 publications. |
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经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Thr18-Asn334
|
Tag | C-His |
Predicted MW | 36.8 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mMTris-HCl,150mMNaCl,pH 8.0. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_034114 |
Locus ID | 13039 |
UniProt ID | P06797, Q543M3 |
Refseq Size | 1971 |
Cytogenetics | 13 33.26 cM |
Refseq ORF | 1002 |
Synonyms | 1190035F06Rik; CatL; Ctsl1; fs; ME; MEP; nkt |
Summary | This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. [provided by RefSeq, Aug 2015] |
Citations (4)
The use of this Proteins has been cited in the following citations: |
---|
Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors.
,null,
European journal of medicinal chemistry
,PubMed ID 30802730
[Ctsl]
|
Posttranslational Regulation of Human DNA Polymerase ι *
,null,
The Journal of Biological Chemistry
,PubMed ID 26370087
[Ctsl]
|
Lisdexamfetamine prodrug activation by peptidase-mediated hydrolysis in the cytosol of red blood cells
,null,
Neuropsychiatric Disease and Treatment
,PubMed ID 25489246
[Ctsl]
|
Biochemical, Proteomic, Structural, and Thermodynamic Characterizations of Integrin-linked Kinase (ILK)
,null,
The Journal of Biological Chemistry
,PubMed ID 21524996
[Ctsl]
|
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