DCK (NM_000788) Human Recombinant Protein
CAT#: TP720869XL
Purified recombinant protein of Human deoxycytidine kinase (DCK)
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CNY 26,600.00
货期*
2周
规格
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经常一起买 (1)
DCK mouse monoclonal antibody, clone OTI16G6 (formerly 16G6)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Leu260
|
Tag | N-His&T7 |
Predicted MW | 34 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, pH 7.5. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_000779 |
Locus ID | 1633 |
UniProt ID | P27707, F5CTF3 |
Refseq Size | 2618 |
Cytogenetics | 4q13.3 |
Refseq ORF | 780 |
Summary | Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Purine metabolism, Pyrimidine metabolism |
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