ketohexokinase (KHK) (NM_000221) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Val298
Tag	C-His
Predicted MW	33.7 kDa
Purity	>95% as determined by SDS-PAGE and Coomassie blue staining
Buffer	Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 50mM KCl, 10% Glycerol, pH 7.4.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability	Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Endotoxin	Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq	NP_000212
Locus ID	3795
UniProt ID	P50053
Refseq Size	2433
Cytogenetics	2p23.3
Refseq ORF	894
Summary	This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Fructose and mannose metabolism, Metabolic pathways

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