United States
Germany
Japan
United Kingdom
China
CD22 Human Recombinant Protein
CAT＃: TP723928
Human CD22 Protein, hFc-His Tag
View other "CD22" proteins (11)
|
Need it in bulk or customized? Get a free quote |
CNY 5,876.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence |
CD22（Asp20-Arg687）+hFc（Glu99-Ala330）+6×His tag
|
| Tag | C-Human Fc and 6×His |
| Predicted MW | 102.1 kDa |
| Purity | > 95% |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Preparation | Affinity purification |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Reference Data | |
| Locus ID | 933 |
| UniProt ID | P20273 |
| Summary | B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | B cell receptor signaling pathway, Cell adhesion molecules (CAMs), Hematopoietic cell lineage |
Documents
| FAQs |
| SDS |
Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC434364 | CD22 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LY434364 | Transient overexpression lysate of CD22 molecule (CD22), transcript variant 4 |
CNY 4,840.00 |
|
| PH316939 | CD22 MS Standard C13 and N15-labeled recombinant protein (NP_001762) |
CNY 19,520.00 |
|
| TP316939 | Recombinant protein of human CD22 molecule (CD22), 20 µg |
CNY 2,900.00 |
|
| TP721302 | Human CD22 Protein (C-His) |
CNY 2,450.00 |
|
| TP721303 | Human CD22 Protein (C-His-Avi) |
CNY 2,450.00 |
|
| TP721304 | Biotinylated Human CD22 Protein (C-His-Avi) |
CNY 3,480.00 |
|
| TP721305 | PE Conjugated Human CD22 Protein (C-His) |
CNY 3,480.00 |
|
| TP721306 | APC Conjugated Human CD22 Protein (C-His) |
CNY 3,480.00 |
|
| TP721307 | Human CD22 Protein (C-Fc) |
CNY 2,450.00 |
|
| TP762390 | Purified recombinant protein of Human CD22 molecule (CD22), transcript variant 1, Asp20-Ala330, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 1,950.00 |
