NCR3 Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) NKp30（Leu19-Glu135）+hFc（Glu99-Ala330）
Tag	C-Human Fc
Predicted MW	39.0 kDa
Purity	> 95%
Buffer	Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Preparation	Affinity purification
Applications	ELISA
Storage	Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing.
Stability	12 months from date of despatch
Reference Data
Locus ID	259197
UniProt ID	O14931
Summary	The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Protein Families	ELISA
Protein Pathways	Natural killer cell mediated cytotoxicity

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