Human ITGAV & ITGB1 Heterodimer Protein, His Tag & hFc Tag
CAT#: TP724068
Human ITGAV & ITGB1 Heterodimer Protein, His Tag & hFc Tag
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CNY 9,270.00
货期*
2周
规格
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Specifications
Product Data | |
Expression Host | HEK293 |
Tag | C-6×His tag and C-Human Fc |
Predicted MW | The protein has a predicted molecular mass of 107.1 & 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGAV-His & ITGB1-hFc is approximately 130-250 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Storage | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Stability | 12 months from date of despatch |
Reference Data | |
Summary | Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. |
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