ALDH1A3 Human Recombinant Protein

CAT#: TP724621

Recombinant Human Aldehyde Dehydrogenase 1-A3/ALDH1A3 (N-His)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Species Human
Protein Source E. coli
Expression cDNA Clone or AA Sequence
Tag N-6His
Buffer Lyophilized from a 0.2 um filtered solution of 20mM HEPES, 150mM KCl,1mM β-ME,0.5mM EDTA,pH7.5.
Note Recombinant Human Aldehyde Dehydrogenase 1-A3 is produced by E.coli. The target gene encoding Met1-Pro512 is expressed with a 6His tag at the N terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 220
UniProt ID P47895
Synonyms Aldehyde dehydrogenase family 1 member A3; ALDH1A3; Aldehyde dehydrogenase 6;Retinaldehyde dehydrogenase 3; RALDH-3; ALDH6
Summary Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. It is required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. Recent studies showed ALDH1A3 could also be used as a marker of cancer stem cells to predict metastasis or clinical prognosis in many cancers.
Protein Families Druggable Genome
Protein Pathways Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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