LOXL2 Human Recombinant Protein

CAT#: TP724638

Recombinant Human Lysyl Oxidase Homolog 2/LOXL2 (N-His)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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经常一起买 (1)
LOXL2 mouse monoclonal antibody, clone OTI2A7 (formerly 2A7)
    • 100 ul

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Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag N-8His
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note Recombinant Human Lysyl Oxidase Homolog 2 is produced by Human 293 Cells. The target gene encoding Q26-Q774 is expressed with a 8His tag at the N terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 4017
UniProt ID Q9Y4K0
Synonyms Lysyl oxidase homolog 2; Lysyl oxidase-like protein 2; Lysyl oxidase-related protein 2; Lysyloxidase-related protein WS9-14; LOXL2
Summary Lysyl oxidase homolog 2 (LOXL2) is a secreted protein that belongs to the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin. LOXL2 is expressed in many tissues, with the highest expression in reproductive tissues, placenta, uterus and prostate, and is up-regulated in a number of cancers cells and tissues. LOXL2 changes the structure of histones and thus changes the shape of the cells, making it easier for the cancer cells to metastasize. LOXL2 expression could also be used as a molecular target in the prevention of breast cancer progression.
Protein Families Druggable Genome, Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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