IGFBP3 Human Recombinant Protein

CAT#: TP724640

Recombinant Human Insulin-like Growth Factor Binding Protein 3/IGFBP3 (C-hFc)



Need it in bulk or customized?
Get a free quote

CNY 3,140.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (1)
IGFBP3 mouse monoclonal antibody, clone OTI3B9 (formerly 3B9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag C-hFc
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note Recombinant Human Insulin-like Growth Factor Binding Protein 3 is produced by Human 293 Cells. The target gene encoding G28-K291 is expressed with a hFc tag at the C terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 3486
UniProt ID P17936
Synonyms acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; growth hormone-dependent binding protein; IBP-3; IBP3BP-53; IGF-binding protein 3; IGFBP3; IGFBP-3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3
Summary Insulin-like growth factor-binding protein 3 (IGFBP3) is a member of IGF binding protein superfamily. IGF binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. IGFBP3 is expressed by most tissues and the expression levels are higher during development. It is up-regulated in the presence of IGF1, insulin and other growth-stimulating factors such as growth hormone, EGF and phorbol esters. IGFBP3 is the most abundant IGF binding protein in human serum and has been shown to be a growth inhibitory, apoptosis-inducing molecule, capable of acting via IGF-dependent and IGF-independent mechanisms. Several clinical studies have shown that individuals with IGFBP3 levels in the upper range of normal may have a decreased risk for certain common cancers
Protein Families Druggable Genome, Secreted Protein
Protein Pathways p53 signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Customer Reviews 
Loading...