Annexin A1 (ANXA1) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A2-N346
Tag	C-Avi&6His
Buffer	Lyophilized from a 0.2 um filtered solution of 2umM Na2HPO4, 2umM NaH2PO4, pH7.4.
Note	Biotinylated Recombinant Human Annexin A1 is produced by E.coli. The target gene encoding A2-N346 is expressed with an Avi and 6His tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	301
UniProt ID	P04083
Synonyms	Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I;Phospholipase A2 Inhibitory Protein; p35
Summary	Annexin A1 is a member of the annexin family that can bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 is found in the cytoplasm, on the cell surface, and in the extracellular fluid. Annexin A1 has anti-inflammatory activities and inhibits phospholipase A2 function. Annexin A1 is also involved in membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. It can exert both positive and negative effects on epithelial?mesenchymal transition and tumor metastasis.
Protein Families	Druggable Genome

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