Mouse Recombinant Protein
CNY 3,140.00
货期*
5周
规格
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Specifications
Product Data | |
Species | Mouse |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Arg24-Thr262
|
Tag | C-His |
Buffer | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Note | Recombinant Mouse SIGLEC-15 (C-His) is produced by Human Cells. The target gene encoding Arg24-Thr262 is expressed with a C-His tag. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Synonyms | CD33 antigen-like 3,SIGLEC-15,CD33L3,sialic acid-binding Ig-like lectin 15,Siglec15,Siglec-15 |
Summary | Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. |
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