P cadherin (CDH3) Human Recombinant Protein

CAT#: TP724791

Recombinant Human Cadherin-3/CDH3 (C-His)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag C-6His
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note Recombinant Human Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu25-Gly654 is expressed with a 6His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 1001
UniProt ID P22223
Synonyms Cadherin-3; Placental Cadherin; P-Cadherin; CDH3; CDHP
Summary Cadherin-3 (CDH3), also known as placental cadherin, is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is expressed in some normal epithelial tissues and some carcinoma cell lines. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. It preferentially binds to one another in a homophilic manner. CDH3 plays a role in development, specifically in tissue formation. CDH3 is also involved in the loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congenital hypotrichosis with juvenile macular dystrophy.
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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