IL23 (IL23A) Human Recombinant Protein

CAT#: TP724835

Recombinant Human IL-23 (C-His)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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IL-23 p19 Rabbit Polyclonal (C-Terminus) Antibody
    • 50 ug

CNY 6,721.00

Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Arg20-Pro189 & Ile23-Ser328
Tag C-6His
Buffer Lyophilized from a 0.2 um filtered solution of PBS, 0.01%Tween 80, pH7.4
Note Recombinant Human Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Arg20-Pro189&Ile23-Ser328 is expressed with a 6His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 51561
UniProt ID Q9NPF7
Synonyms Interleukin-23; IL-23; SGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2
Summary Interleukin 23 (IL-23) is a member of the IL-12 family of cytokines. IL-23 is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single-chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. While p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, p40 is only expressed by activated macrophages and dendritic cells. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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