Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Leu441
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.5
Note	Recombinant Human Tau is produced by our E.coli expression system and the target gene encoding Met1-Leu441 is expressed.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Synonyms	Microtubule-associated protein tau; MAPTL; Neurofibrillary tangle protein; MTBT1; Paired helical filament-tau; MAPT; Tau-F; MAPT-F
Summary	Tau is a microtubule-associated protein expressed primarily in neurons. Tau promotes the assembly and stabilization of microtubules along with other MAP proteins. It is thought that other proteins can compensate for the loss of Tau protein function as Tau knockout mice are viable and show no signs of neurodegeneration. There are multiple isoforms of Tau created by alternative splicing of exons 2, 3, and 10. When tau proteins are defective and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.