Eph receptor A2 (EPHA2) Human Recombinant Protein

CAT#: TP725154

Recombinant Human EphA2 (C-Fc)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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经常一起买 (1)
EPHA2 rabbit polyclonal antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag C-hFc
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note Recombinant Human EphA2 is produced by our Mammalian expression system and the target gene encoding Ala24-Asn534 is expressed with a hFc tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 1969
UniProt ID P29317
Synonyms Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; EPHA2
Summary Ephrin type-A receptor 2 (EphA2) belongs to the Eph receptor tyrosine kinase family which binds Ephrins A1, 2, 3, 4, and 5. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural topographic maps. They have also been found involved in embryonic patterning, neuronal targeting, vascular development and adult neovascularization. Furthermore, elevated expression of Eph receptors and ephrin ligands is associated with tumors and associated tumor vasculature, suggesting the Eph receptors and ephrin ligands also play critical roles in tumor angiogenesis and tumor growth. EphA2 is upregulated in breast, prostate, and colon cancer vascular endothelium. Its ligand, EphrinA1, is expressed by the local tumor cells. In some cases, EphA2 and EphrinA1 are expressed in the same blood vessels. EphA2 signaling cooperates with VEGF receptor signaling in promoting endothelial cell migration.
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Axon guidance
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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