LILRB1 Human Recombinant Protein

CAT#: TP725291

Recombinant Human LILRB1/ILT2/CD85j (C-Fc)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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经常一起买 (1)
Rabbit Polyclonal Anti-LILRB1 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag C-hFc
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note Recombinant Human LILRB1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a hFc tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 10859
UniProt ID Q8NHL6
Synonyms Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; CD85 Antigen-Like Family Member J; Immunoglobulin-Like Transcript 2; ILT-2; Monocyte/Macrophage Immunoglobulin-Like Receptor 7; MIR-7; CD85j; LILRB1; ILT2; LIR1; MIR7
Summary CD85 antigen-like family member J (CD85J) is an essential mediator of immune activation and tolerance that is the member of the leukocyte immunoglobulin-like receptor (LIR) family. CD85J is primarily expressed on B-cells and monocytes. CD85J is a receptor for a variety of major histocompatibility complex class I molecules (MHCIs) and transduces negative signals and down-regulation of the immune response. The transcription level of CD85J is associated with surface protein expression on NK cells. CD85J can interact with HLA-B or HLA-E and lead to inhibition of the signal triggered by FCER1A and inhibits serotonin release. In addition, CD85J inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Protein Families Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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