BAX Human Recombinant Protein
CNY 3,140.00
货期*
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经常一起买 (1)
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Specifications
Product Data | |
Species | Human |
Protein Source | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Gln171
|
Tag | N-6His, C-6His |
Buffer | Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,2mM EDTA,5% Trehalose,30% Glycerol,pH7.4 |
Note | Recombinant Human BCL2-associated X protein is produced by our E.coli expression system and the target gene encoding Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus. |
Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 581 |
UniProt ID | Q07812 |
Synonyms | Bax; BCL2-associated X protein; Bcl2-L-4; BCL2L4 |
Summary | The Human Bax protein is a part of the anti-apoptotic BCL-2 family. This protein can transform from a cytosolic monomer into a dangerous mitochondrial oligomer. The Bax protein activates and transforms into a lethal oligomer that causes mitochondrial outer membrane permeabilization which commits human cells to apoptosis. |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, Neurotrophin signaling pathway, p53 signaling pathway, Pathways in cancer, Prion diseases |
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