beta 2 Microglobulin (B2M) Human Recombinant Protein

CAT#: TP726739

Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)



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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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B2M mouse monoclonal antibody,clone 1A9, Magnetic Beads
    • 1 ml

CNY 7,700.00

Specifications

Product Data
Species Human
Protein Source Human
Expression cDNA Clone or AA Sequence
Ile21-Met119&Gly25-Ile308 (Ala269Val)
Tag C-10His
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 500mM NaCl, pH7.4.
Note Recombinant Human B2M&HLA-A is produced by our Mammalian expression system and the target gene encoding Ile21-Met119&Gly25-Ile308 (Ala269Val) is expressed with a 10His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 567
UniProt ID P61769
Synonyms MHC; MY-ESO-1
Summary NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Antigen processing and presentation
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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