Glypican 3 (GPC3) Human Recombinant Protein
CAT#: TP726800
Recombinant Human Glypican 3/GPC3/OCI5 (C-6His)
Need it in bulk or customized? Get a free quote |
CNY 3,140.00
货期*
2周
规格
Product images
经常一起买 (1)
GPC3 mouse monoclonal antibody,clone OTI1G5
CNY 1,999.00
CNY 3,600.00
Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Gln25-His559
|
Tag | C-His |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Note | Recombinant Human Glypican-3 is produced by our Mammalian expression system and the target gene encoding Gln25-His559 is expressed with a 6His tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 2719 |
UniProt ID | P51654 |
Synonyms | Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7; GPC3; OCI5 |
Summary | Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms such as hepatocellular carcinoma, malignant melanoma, and testicular yolk sac tumor, and plays an important role in cell growth and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a tumor suppressor gene, whereas in others, it acts as an oncofetal protein. GPC3 is a reliable marker for hepatocellular carcinoma. The sensitivity and specificity exceeds both alpha-fetoprotein and hepatocyte-paraffin1. GPC3 immunohistochemistry can aid in the differentiation of testicular germ cell tumors, being expressed in all yolk sac tumors but not in seminomas. |
Protein Families | Druggable Genome |
Documents
FAQs |
SDS |
其它Glypican 3产品
Customer
Reviews
Loading...