Il13ra1 Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ala25-Thr340
Tag	C-AVI&His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Note	Biotinylated Recombinant Mouse Interleukin-13 receptor subunit alpha-1 is produced by our Mammalian expression system and the target gene encoding Ala25-Thr340 is expressed with a AVI, 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	16164
UniProt ID	O09030
Synonyms	Interleukin-13 receptor subunit alpha-1;IL-13RA1;Interleukin-13-binding protein;Novel cytokine receptor 4;NR4;CD213a1
Summary	Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13(IL3). IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. The WSXWS motif in domains appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.

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