Selenophosphate synthetase 1 (SEPHS1) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Ser392
Tag	C-His
Buffer	Supplied as a 0.2 um filtered solution of 25mM Tris-HCl, 100mM glycine, 10% Glycerol, pH 7.3.
Note	Recombinant Human Selenophosphate synthase is produced by our Mammalian expression system and the target gene encoding Met1-Ser392 is expressed with a 6His tag at the C-terminus.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Locus ID	22929
UniProt ID	P49903
Synonyms	Selenide; water dikinase 1;Selenium donor protein 1;Selenophosphate synthase 1;SEPHS1;SELD; SPS; SPS1
Summary	Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.
Protein Families	Stem cell - Pluripotency
Protein Pathways	Metabolic pathways, Selenoamino acid metabolism

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