GDNF Receptor alpha 2 (GFRA2) Human Recombinant Protein

CAT#: TP727244

Recombinant Human GDNF Receptor α-2/GFRA2 (C-Fc-6His)



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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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经常一起买 (1)
Rabbit Polyclonal Anti-GFRA2 Antibody
    • 50 ug

CNY 4,628.00

Specifications

Product Data
Species Human
Protein Source Human
Expression cDNA Clone or AA Sequence
Tag C-Fc&His
Buffer Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Note Recombinant Human Glial Cell line-derived Neurotrophic Factor Receptor alpha 2 is produced by our Mammalian expression system and the target gene encoding Ser22-Ser441 is expressed with a Fc, 6His tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 2675
UniProt ID O00451
Synonyms GDNFR-beta;Neurturin receptor alpha;RET ligand 2;TGF-beta-related neurotrophic factor receptor 2;GDNFRB; RETL2; TRNR2
Summary GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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