Factor X (F10) Human Recombinant Protein
CAT#: TP727809
Recombinant Human Coagulation Factor X (C-Fc)
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CNY 3,140.00
货期*
2周
规格
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经常一起买 (1)
F10 mouse monoclonal antibody,clone OTI1D12
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Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Asn32-Lys488
|
Tag | C-Fc |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM MES, 150mM NaCl, 0.2mM CaCl2, pH5.5. |
Note | Recombinant Human Coagulation Factor X is produced by our Mammalian expression system and the target gene encoding Asn32-Lys488 is expressed with a Fc tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 2159 |
UniProt ID | P00742 |
Synonyms | Coagulation factor X; Stuart factor; Stuart-Prower factor |
Summary | F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41‑179) and heavy (residues 235‑488) chains linked by a disulfide bond. Coagulation factor X is initially synthesized in the liver. The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. Forms a heterodimer with SERPINA5. F10 is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
Protein Families | Druggable Genome, Protease, Transmembrane |
Protein Pathways | Complement and coagulation cascades |
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