Dectin 1 (CLEC7A) Human Recombinant Protein

CAT#: TP727831

Recombinant Human Dectin-1 (N-Fc)



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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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Rabbit Polyclonal CLEC7A Antibody
    • 100 ug

CNY 5,808.00

Specifications

Product Data
Species Human
Protein Source Human
Expression cDNA Clone or AA Sequence
Tag N-Fc
Buffer Lyophilized from a 0.2 um filtered solution of PBS,pH7.4.
Note Recombinant Human C-type lectin domain family 7 member A is produced by our Mammalian expression system and the target gene encoding Thr66-Met247 is expressed with a Fc tag at the N-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 64581
UniProt ID Q9BXN2
Synonyms Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1;Dectin1; Dectin-1; DECTIN1CANDF4
Summary Dectin-1 was recently identified as the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against opportunistic fungal infection.
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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