Siglec 7 (SIGLEC7) Human Recombinant Protein
CNY 3,140.00
货期*
2周
规格
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经常一起买 (1)
SIGLEC7 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Gln19-Leu353
|
Tag | C-6His |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Note | Recombinant Human Sialic Acid-binding Ig-like lectin 7 is produced by our Mammalian expression system and the target gene encoding Gln19-Leu353 is expressed with a 6His tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 27036 |
UniProt ID | Q9Y286 |
Synonyms | siglec-7; AIRM1; AIRM-1; AIRM1QA79 membrane protein; CD328 antigen; CD328; CDw328; D-siglec; p75; p75/AIRM1; QA79; sialic acid binding Ig-like lectin 7; sialic acid-binding Ig-like lectin 7; Siglec7; Siglec-7 |
Summary | Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Eleven human Siglecs have been cloned and characterized. Human Siglec-7 encodes a 467 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail. Siglec-7 exists as a monomer on the cell surface and is expressed on natural killer cells, CD8+ T cells and monocytes. It binds equally well to both alpha 2,3- and alpha 2,6-linked sialic acid. The gene encoding Siglec-7 was mapped to chromosome 19q13.3. |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
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