BNP (NPPB) (NM_002521) Human Recombinant Protein

CAT#: TP750121

Purified recombinant protein of Human natriuretic peptide B (NPPB), N-terminal His and ABP tag, expressed in E. coli, 50ug



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CNY 2,000.00


货期*
现货

规格
    • 50 ug

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经常一起买 (1)
NPPB mouse monoclonal antibody, clone OTI11G4 (formerly 11G4)
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(His27-Arg102) of NPPB
Tag N-His-ABP (Albumin-Binding Protein)
Predicted MW 23.8 kDa
Concentration >0.05 µg/µL as determined by Bradford protein assay method.
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002512
Locus ID 4879
UniProt ID P16860
Refseq Size 708
Cytogenetics 1p36.22
Refseq ORF 402
Synonyms BNP; Iso-ANP
Summary This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, Secreted Protein, Stem cell - Pluripotency
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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