TRIM72 (NM_001008274) Human Recombinant Protein

CAT#: TP750134

Purified recombinant protein of Human MG53,Met1-Asp270, expressed in E. coli,50ug



  View other "TRIM72" proteins (9)

Need it in bulk or customized?
Get a free quote

CNY 3,010.00


货期*
2周

规格
    • 50 ug

Product images

经常一起买 (1)
MG53 Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region Met1-Asp270 of MG53
Tag Tag Free
Predicted MW 29.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 85% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Endotoxin < 1 EU per 1 µg of the protein by the LAL
Reference Data
RefSeq NP_001008275
Locus ID 493829
UniProt ID Q6ZMU5
Refseq Size 2098
Cytogenetics 16p11.2
Refseq ORF 1431
Synonyms MG53
Summary Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...